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USP7-IN-8
CAS No. 2009273-60-1
USP7-IN-8( GNE-6776 )
Catalog No. M23902 CAS No. 2009273-60-1
USP7-IN-8 is a selective ubiquitin-specific protease 7 (USP7) inhibitor with an IC50 of 1.4 μM. USP7-IN-8 has anticancer effects.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 147 | In Stock |
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| 10MG | 237 | In Stock |
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| 25MG | 447 | In Stock |
|
| 50MG | 651 | In Stock |
|
| 100MG | 888 | In Stock |
|
| 500MG | 1782 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameUSP7-IN-8
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NoteResearch use only, not for human use.
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Brief DescriptionUSP7-IN-8 is a selective ubiquitin-specific protease 7 (USP7) inhibitor with an IC50 of 1.4 μM. USP7-IN-8 has anticancer effects.
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DescriptionUSP7-IN-8 is a selective ubiquitin-specific protease 7 (USP7) inhibitor with an IC50 of 1.4 μM. USP7-IN-8 has anticancer effects.
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In VitroUSP7 or HAUSP (herpesvirus-associated USP) is a ubiquitin specific protease or a deubiquitylating enzyme that cleaves ubiquitin from its substrates. USP7 is a eubiquitinase (DUB) that controls cell proliferation by altering the stability of Mdm2, p53, PTEN and FOXO4.
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In Vivo——
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SynonymsGNE-6776
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PathwayProteasome/Ubiquitin
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TargetDUB
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RecptorUSP7
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Research Area——
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Indication——
Chemical Information
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CAS Number2009273-60-1
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Formula Weight348.4
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Molecular FormulaC20H20N4O2
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Purity>98% (HPLC)
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SolubilityDMSO:80mg/ml(230.08mM; need ultrasonic)
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SMILESCCc(c(-c(cc1)ccc1O)c(N)nc1)c1-c(cc1)cnc1C(NC)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Blake R , Lello P D , Drummond J , et al. USP7 INHIBITOR COMPOUNDS AND METHODS OF USE:, US20160272588[P]. 2016.
molnova catalog
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