MF-094( MF094 )

Catalog No. M13591 CAS No. 2241025-68-1

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

MF-094
Note

Research use only, not for human use.
Brief Description

MF-094 (MF094) is a potent, highly selective inhibitor of ubiquitin specific protease 30 (USP30) with IC50 of 0.12 uM.
Description

MF-094 (MF094) is a potent, highly selective inhibitor of ubiquitin specific protease 30 (USP30) with IC50 of 0.12 uM, demonstrates <30% inhibitory activity for a panel of 22 USPs assays at 10 uM; increases protein ubiquitination and accelerates mitophagy.
In Vitro

MF-094 has <30% inhibitory activity for a panel of 22 USPs assays at 10 uM.
In Vivo

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Synonyms

MF094
Pathway

Proteasome/Ubiquitin
Target

DUB
Recptor

DUB
Research Area

——
Indication

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CAS Number

2241025-68-1
Formula Weight

535.703
Molecular Formula

C30H37N3O4S
Purity

>98% (HPLC)
Solubility

DMSO : 125 mg/mL 233.34 mM
SMILES

CC(C)(C)NS(=O)(=O)C1=CC=CC2=C1C=CC=C2NC(=O)C(CC3=CC=CC=C3)NC(=O)C4CCCCC4
Chemical Name

(S)-N-(1-((5-(N-(tert-butyl)sulfamoyl)naphthalen-1-yl)amino)-1-oxo-3-phenylpropan-2-yl)cyclohexanecarboxamide

1. Kluge AF, et al. Bioorg Med Chem Lett. 2018 May 8. pii: S0960-894X(18)30402-5.

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