Home - Products - Proteasome/Ubiquitin - DUB - USP8-IN-2

USP8-IN-2

CAS No. 2477651-11-7

USP8-IN-2( —— )

Catalog No. M36043 CAS No. 2477651-11-7

USP8-IN-2 is a potent inhibitor of the deubiquitinating enzymes USP7 and USP8, with an IC50 of 4.0 μM against USP8D. USP8-IN-2 is a potential compound for the treatment of cancer and viral infections.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
2MG	137	Get Quote
5MG	211	Get Quote
10MG	330	Get Quote
25MG	531	Get Quote
50MG	757	Get Quote
100MG	981	Get Quote
500MG	Get Quote	Get Quote
1G	Get Quote	Get Quote

Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

USP8-IN-2
Note

Research use only, not for human use.
Brief Description

USP8-IN-2 is a potent inhibitor of the deubiquitinating enzymes USP7 and USP8, with an IC50 of 4.0 μM against USP8D. USP8-IN-2 is a potential compound for the treatment of cancer and viral infections.
Description

USP8-IN-2 (Compd U52) is a deubiquitinase USP8 inhibitor with an IC50 value of 6.0 μM. USP8-IN-2 also inhibits the proliferation of H1957 cells with an GI50 value of 24.93 μM, respectively.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Proteasome/Ubiquitin
Target

DUB
Recptor

DUB
Research Area

——
Indication

——

Chemical Information

CAS Number

2477651-11-7
Formula Weight

444.9
Molecular Formula

C19H20ClF3N4OS
Purity

>98% (HPLC)
Solubility

——
SMILES

C(F)(F)(F)C1=NC(=CC=C1)N2CCC(NC(NC3=C(OC)C=CC(Cl)=C3)=S)CC2
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Li zhiyun, et al. Preparing method and application of USP8 inhibitor: China, CN111138358 A. 2020-05-12.

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

related products

Ubiquitin Isopeptida...

A small molecule inhibitor of ubiquitin-proteasome system by inhibiting the ubiquitin isopeptidases.
MK8745

MK-8745 is a potent and selective Aurora A inhibitor.
SJB3-019A B

SJB3-019A is a potent, potent and novel ubiquitin-specific protease 1 (USP1) inhibitor, which promotes ID1 degradation and cytotoxicity in K562 cells 5 times more than SJB2-043, with IC50 of 0.0781 μM. SJB3-019A inhibits cell proliferation and causes cell apoptosis.

Sign In Join Free