RITA ( NSC 652287 )

Catalog No. M13397 CAS No. 213261-59-7

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Datasheet

HNMR

HPLC

MSDS

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Product Name

RITA
Note

Research use only, not for human use.
Brief Description

RITA(NSC 652287) induced both DNA-protein and DNA-DNA cross-links with no detectable DNA single-strand breaks. RITA, a drug that, like nutlin-3, can disrupt the p53/Mdm2 interaction.
Description

RITA(NSC 652287) induced both DNA-protein and DNA-DNA cross-links with no detectable DNA single-strand breaks. RITA, a drug that, like nutlin-3, can disrupt the p53/Mdm2 interaction.
In Vitro

——
In Vivo

——
Synonyms

NSC 652287
Pathway

Apoptosis
Target

MDM2-p53
Recptor

Mdm2| p53
Research Area

Cancer
Indication

——

CAS Number

213261-59-7
Formula Weight

292.37
Molecular Formula

C14H12O3S2
Purity

>98% (HPLC)
Solubility

Ethanol: 8 mg/mL (27.36 mM); DMSO: 58 mg/mL (198.37 mM)
SMILES

OCC1=CC=C(C2=CC=C(C3=CC=C(CO)S3)O2)S1
Chemical Name

[5-[5-[5-(hydroxymethyl)thiophen-2-yl]furan-2-yl]thiophen-2-yl]methanol

1.Ma T, et al. Biochem Biophys Res Commun. 2012, 417(3), 931-937.

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