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RITA
CAS No. 213261-59-7
RITA ( NSC 652287 )
Catalog No. M13397 CAS No. 213261-59-7
RITA(NSC 652287) induced both DNA-protein and DNA-DNA cross-links with no detectable DNA single-strand breaks. RITA, a drug that, like nutlin-3, can disrupt the p53/Mdm2 interaction.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 34 | In Stock |
|
| 5MG | 55 | In Stock |
|
| 10MG | 87 | In Stock |
|
| 25MG | 178 | In Stock |
|
| 50MG | 327 | In Stock |
|
| 100MG | 482 | In Stock |
|
| 200MG | 677 | In Stock |
|
| 500MG | 1035 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameRITA
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NoteResearch use only, not for human use.
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Brief DescriptionRITA(NSC 652287) induced both DNA-protein and DNA-DNA cross-links with no detectable DNA single-strand breaks. RITA, a drug that, like nutlin-3, can disrupt the p53/Mdm2 interaction.
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DescriptionRITA(NSC 652287) induced both DNA-protein and DNA-DNA cross-links with no detectable DNA single-strand breaks. RITA, a drug that, like nutlin-3, can disrupt the p53/Mdm2 interaction.
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In Vitro——
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In Vivo——
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SynonymsNSC 652287
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PathwayApoptosis
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TargetMDM2-p53
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RecptorMdm2| p53
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number213261-59-7
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Formula Weight292.37
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Molecular FormulaC14H12O3S2
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Purity>98% (HPLC)
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SolubilityEthanol: 8 mg/mL (27.36 mM); DMSO: 58 mg/mL (198.37 mM)
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SMILESOCC1=CC=C(C2=CC=C(C3=CC=C(CO)S3)O2)S1
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Chemical Name[5-[5-[5-(hydroxymethyl)thiophen-2-yl]furan-2-yl]thiophen-2-yl]methanol
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Ma T, et al. Biochem Biophys Res Commun. 2012, 417(3), 931-937.
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