p53-MDM2-IN-1

CAS No. 381717-91-5

p53-MDM2-IN-1( —— )

Catalog No. M36397 CAS No. 381717-91-5

p53-MDM2-IN-1 (Example 30), an inhibitor of the p53-MDM2/X protein interaction, exhibits a K i value of 23.35 μM and holds potential for applications in anti-tumor research.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 278 In Stock
10MG 408 In Stock
25MG 620 In Stock
50MG 826 In Stock
100MG 1097 In Stock
200MG 1469 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    p53-MDM2-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    p53-MDM2-IN-1 (Example 30), an inhibitor of the p53-MDM2/X protein interaction, exhibits a K i value of 23.35 μM and holds potential for applications in anti-tumor research.
  • Description
    p53-MDM2-IN-1 (Example 30) is an inhibitor of p53-MDM2/X protein interaction with an Ki value of 23.35 μM. p53-MDM2-IN-1 can be used for anti-tumor research.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    MDM2-p53
  • Recptor
    Mdm2 | p53
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    381717-91-5
  • Formula Weight
    421.88
  • Molecular Formula
    C23H20ClN3O3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(=O)(C=1C(N(CCCN2C=CN=C2)C(=O)C1O)C3=CC=C(Cl)C=C3)C4=CC=CC=C4
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Zhang W, et al. Pyrrylketone compound and application thereof as drug. China. CN102603717.
molnova catalog
related products
  • SM13

    SM13 is a novel small molecule that blocks p53-MDM2 interaction and induces apoptosis both in vitro and in vivo.

  • CP-31398 dihydrochlo...

    CP-31398 is a small molecule p53 reactivator that protects p53 from thermal denaturation.

  • MMRi6

    MMRi6 is a small molecule inhibitor that disrupts Mdm2-MdmX RING-RING interaction interactions in vitro and activates p53 in cancer cells.