Tiotropium bromide( Tiopropium )

Catalog No. M11497 CAS No. 136310-93-5

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Tiotropium bromide
Note

Research use only, not for human use.
Brief Description

A long-acting muscarinic receptor antagonist that used in the management of chronic obstructive pulmonary disease (COPD).
Description

A long-acting muscarinic receptor antagonist that used in the management of chronic obstructive pulmonary disease (COPD).COPD Approved(In Vitro):Tiotropium Bromide stops signaling between neurons and leads to muscle relaxation. Tiotropium Bromide is a long-acting, 24 hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease. Tiotropium Bromide improves symptoms of chronic obstructive pulmonary disease complicated by chronic heart failure.
In Vitro

Tiotropium Bromide stops signaling between neurons and leads to muscle relaxation. Tiotropium Bromide is a long-acting, 24 hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease. Tiotropium Bromide improves symptoms of chronic obstructive pulmonary disease complicated by chronic heart failure.
In Vivo

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Synonyms

Tiopropium
Pathway

GPCR/G Protein
Target

mAChR
Recptor

mAChR
Research Area

Inflammation/Immunology
Indication

COPD

CAS Number

136310-93-5
Formula Weight

472.4163
Molecular Formula

C19H22BrNO4S2
Purity

>98% (HPLC)
Solubility

DMSO: ≥ 30 mg/mL
SMILES

C[N+]1([C@@H]2CC(C[C@H]1[C@H]3[C@@H]2O3)OC(=O)C(C4=CC=CS4)(C5=CC=CS5)O)C.[Br-]
Chemical Name

3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane, 7-[(2-hydroxy-2,2-di-2-thienylacetyl)oxy]-9,9-dimethyl-, bromide (1:1), (1α,2β,4β,5α,7β)-

1. Kato M, et al. Circ J. 2006 Dec;70(12):1658-60. 2. Singh S, et al. BMJ. 2011 Jun 14;342:d3215.

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