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PF-3635659
CAS No. 931409-24-4
PF-3635659( PF-03635659 )
Catalog No. M16665 CAS No. 931409-24-4
PF-3635659 (PF-03635659) is a potent, very long dissociative half-life (slow off-rate, >1440 min) muscarinic M3 antagonist with Ki of 0.2 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 639 | In Stock |
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| 5MG | 561 | In Stock |
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| 10MG | 801 | In Stock |
|
| 25MG | 1216 | In Stock |
|
| 50MG | 1609 | In Stock |
|
| 100MG | 2167 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 4343 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamePF-3635659
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NoteResearch use only, not for human use.
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Brief DescriptionPF-3635659 (PF-03635659) is a potent, very long dissociative half-life (slow off-rate, >1440 min) muscarinic M3 antagonist with Ki of 0.2 nM.
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DescriptionPF-3635659 (PF-03635659) is a potent, very long dissociative half-life (slow off-rate, >1440 min) muscarinic M3 antagonist with Ki of 0.2 nM, shows potential for the treatment of chronic obstructive pulmonary disease (COPD).COPD Phase 2 Discontinued.
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In Vitro——
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In Vivo——
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SynonymsPF-03635659
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PathwayGPCR/G Protein
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TargetmAChR
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RecptormAChR
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Research AreaInflammation/Immunology
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IndicationCOPD
Chemical Information
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CAS Number931409-24-4
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Formula Weight444.58
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Molecular FormulaC28H32N2O3
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(N)C(C1=CC=CC=C1)(C2=CC=CC=C2)CCC(C)(C)N3CC(OC4=CC=CC(O)=C4)C3
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Chemical Name3-(3-hydroxyphenoxy)-delta,delta-dimethyl-alpha,alpha-diphenyl-1-azetidinepentanamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Glossop PA, et al. J Med Chem. 2011 Oct 13;54(19):6888-904.
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