Cart
sales@molnova.com
Home - Products - Apoptosis - Caspase - Procaspase-3 activator 1541B

Procaspase-3 activator 1541B

CAS No. 1170689-68-5

Procaspase-3 activator 1541B( Compound 1541B )

Catalog No. M10573 CAS No. 1170689-68-5

Procaspase-3 activator 1541B is a specific, small molecule activator of procaspases-3 with EC50 of 1.3 uM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 873 Get Quote
50MG 1782 Get Quote
100MG 2250 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Procaspase-3 activator 1541B
  • Note
    Research use only, not for human use.
  • Brief Description
    Procaspase-3 activator 1541B is a specific, small molecule activator of procaspases-3 with EC50 of 1.3 uM.
  • Description
    Procaspase-3 activator 1541B is a specific, small molecule activator of procaspases-3 with EC50 of 1.3 uM; shows no activition activity for procaspases-6; shows considerable synergy in activating procaspase-3 in vitro combined with PAC-1, stimulates rapid and dramatic maturation of procaspase-3 in multiple cancer cell lines; effectively reduces tumor burden in a murine lymphoma model combined with PAC-1, but not treated alone.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Compound 1541B
  • Pathway
    Apoptosis
  • Target
    Caspase
  • Recptor
    Caspase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1170689-68-5
  • Formula Weight
    397.39
  • Molecular Formula
    C23H15N3O4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(C(C1=O)=CC2=C(O1)C(O)=CC=C2)NC3=CC=CC(C4=CN5C=CC=CC5=N4)=C3
  • Chemical Name
    8-hydroxy-N-(3-(imidazo[1,2-a]pyridin-2-yl)phenyl)-2-oxo-2H-chromene-3-carboxamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Wolan DW, et al. Science. 2009 Nov 6;326(5954):853-8. 2. Botham RC, et al. J Am Chem Soc. 2014 Jan 29;136(4):1312-9. 3. Julien O, et al. Nat Chem Biol. 2014 Nov;10(11):969-76.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • VX-765

    VX-765 (Belnacasan) is an orally absorbed prodrug of VRT-043198, which is a potent and selective inhibitor of interleukin-converting enzyme/caspase-1 with Ki of 0.8 nM.

  • MMPSI

    MMPSI (Caspase-3/7 Inhibitor I) is a novel, non-peptide small molecule caspase 3 and caspase 7 inhibitor that reduces ischemic injury in isolated rabbit heart or cardiomyocytes and inhibits apoptosis of H16c2 cells in a concentration-dependent manner.

  • Estramustine phospha...

    Estramustine phosphate sodium is an antimicrotubule chemotherapy agent; arrests prostate cancer cells in the G2/M phase of the cell cycle.

Sign In Join Free