Lucidenic acid B( —— )

Catalog No. M37738 CAS No. 95311-95-8

Lucidenic acid B (Lucidenicacid B), a natural compound extracted from Ganoderma lucidum, induces activation of caspase-9 and caspase-3 and cleavage of PARP, which can induce apoptosis in human leukemia cells through mitochondrial mediation.

Purity : >98% (HPLC)

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Biological Information

Product Name

Lucidenic acid B
Note

Research use only, not for human use.
Brief Description

Lucidenic acid B (Lucidenicacid B), a natural compound extracted from Ganoderma lucidum, induces activation of caspase-9 and caspase-3 and cleavage of PARP, which can induce apoptosis in human leukemia cells through mitochondrial mediation.
Description

Lucidenic acid B is a natural compound isolated from Ganoderma lucidum, induces apoptosis of cancer cells, and causes the activation of caspase-9 and caspase-3, and cleavage of PARP. Lucidenic acid B does not affect the cell cycle profile, or the number of necrotic cells.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Apoptosis
Target

Caspase
Recptor

Caspase | Apoptosis
Research Area

——
Indication

——

Chemical Information

CAS Number

95311-95-8
Formula Weight

474.59
Molecular Formula

C27H38O7
Purity

>98% (HPLC)
Solubility

——
SMILES

C[C@]12C3=C([C@]4(C)[C@@](C[C@@H]3O)(C(C)(C)C(=O)CC4)[H])C(=O)[C@@H](O)[C@]1(C)[C@@]([C@@H](CCC(O)=O)C)(CC2=O)[H]
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Hsu CL, et al. Lucidenic acid B induces apoptosis in human leukemia cells via a mitochondria-mediated pathway. J Agric Food Chem. 2008 Jun 11;56(11):3973-80.?

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