HM03( —— )

Catalog No. M22402 CAS No. 500565-15-1

HM03 is a potent and selective inhibitor of HSPA5, and has anticancer activity.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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10MG	72	Get Quote
25MG	140	Get Quote
50MG	258	Get Quote
100MG	447	Get Quote
200MG	584	Get Quote
500MG	Get Quote	Get Quote
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Biological Information

Product Name

HM03
Note

Research use only, not for human use.
Brief Description

HM03 is a potent and selective inhibitor of HSPA5, and has anticancer activity.
Description

HM03 is a potent and selective inhibitor of HSPA5, and has anticancer activity.
In Vitro

Cell Viability Assay Cell Line:HCT116 cells Concentration:0.1, 1, 10, 25, 50 μM Incubation Time:72 hours Result:Exhibited prominent inhibition effect (18% survival at 25 μM).
In Vivo

——
Synonyms

——
Pathway

Cytoskeleton/Cell Adhesion Molecules
Target

HSP
Recptor

HSPA5
Research Area

——
Indication

——

Chemical Information

CAS Number

500565-15-1
Formula Weight

462.97
Molecular Formula

C26H27ClN4O2
Purity

>98% (HPLC)
Solubility

DMSO:125 mg/mL (270.00 mM; Need ultrasonic)
SMILES

COc1ccc2nc3cc(Cl)ccc3c(Nc3ccc(O)c(CN4CCN(C)CC4)c3)c2c1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Huang M , Li Z , Li D , et al. Structure-based design of HSPA5 inhibitors: From peptide to small molecule inhibitors[J]. Bioorganic & Medicinal Chemistry Letters, 2013, 23(10):3044-3050.

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