Cart
sales@molnova.com
MKT-077
CAS No. 147366-41-4
MKT-077( FJ-776 )
Catalog No. M12027 CAS No. 147366-41-4
MKT-077 (FJ-776) is a highly water-soluble (>200 mg/ml) rhodacyanine dye that exhibits significant antitumor activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 77 | In Stock |
|
| 10MG | 135 | In Stock |
|
| 25MG | 230 | In Stock |
|
| 50MG | 368 | In Stock |
|
| 100MG | 478 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameMKT-077
-
NoteResearch use only, not for human use.
-
Brief DescriptionMKT-077 (FJ-776) is a highly water-soluble (>200 mg/ml) rhodacyanine dye that exhibits significant antitumor activity.
-
DescriptionMKT-077 (FJ-776) is a highly water-soluble (>200 mg/ml) rhodacyanine dye that exhibits significant antitumor activity, binds to Hsp70 family member, mortalin (mot-2), and abrogates its interactions with p53; induces release of wild-type p53 from cytoplasmically sequestered p53-mot-2 complexes and rescued its transcriptional activation function; also is a potent telomerase inhibitor with IC50 of 5 uM.
-
In Vitro——
-
In Vivo——
-
SynonymsFJ-776
-
PathwayCytoskeleton/Cell Adhesion Molecules
-
TargetHSP
-
RecptorHSP70
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number147366-41-4
-
Formula Weight432
-
Molecular FormulaC21H22ClN3OS2
-
Purity>98% (HPLC)
-
SolubilityDMSO: 20 mg/mL; Water: 20 mg/mL （ < 1 mg/ml refers to the product slightly soluble or insoluble )
-
SMILESO=C1N(CC)/C(S/C1=C2SC3=CC=CC=C3N/2C)=C/C4=CC=CC=[N+]4CC.[Cl-]
-
Chemical NamePyridinium, 1-ethyl-2-[[3-ethyl-5-(3-methyl-2(3H)-benzothiazolylidene)-4-oxo-2-thiazolidinylidene]methyl]-, chloride (9CI)
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Koya K, et al. Cancer Res. 1996 Feb 1;56(3):538-43.
2. Wadhwa R, et al. Cancer Res. 2000 Dec 15;60(24):6818-21.
3. Naasani I, et al. Cancer Res. 1999 Aug 15;59(16):4004-11.
molnova catalog
related products
-
CCT-251236
A potent, orally available Pirin ligand (Ki=28 nM), blocks the HSF1-mediated induction of both HSP72 and HSP27.
-
GSK650394
GSK650394 is a serum- and glucocorticoid-regulated kinase-1 inhibitor.
-
AK778
AK778 (Col001) is a small-molecule compound that inhibits the interaction of Hsp47 with collagen.
