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Epolactaene
CAS No. 167782-17-4
Epolactaene( Epolactaene )
Catalog No. M12563 CAS No. 167782-17-4
Epolactaene is a neuritogenic fungal isolate that arrests the cell cycle at the G0/G1 phase and induces the outgrowth of neurites in human neuroblastoma SH-SY5Y cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 1773 | Get Quote |
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| 50MG | 3582 | Get Quote |
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| 100MG | 4950 | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameEpolactaene
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NoteResearch use only, not for human use.
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Brief DescriptionEpolactaene is a neuritogenic fungal isolate that arrests the cell cycle at the G0/G1 phase and induces the outgrowth of neurites in human neuroblastoma SH-SY5Y cells.
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DescriptionEpolactaene is a neuritogenic fungal isolate that arrests the cell cycle at the G0/G1 phase and induces the outgrowth of neurites in human neuroblastoma SH-SY5Y cells; inhibits DNA topoisomerase II (topo II), binds to Hsp60 Cys442 resulting in the inhibition of chaperone activity; also reacts with N-acetylcysteine methyl ester and induces the disulfide formation.
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In Vitro——
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In Vivo——
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SynonymsEpolactaene
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PathwayCytoskeleton/Cell Adhesion Molecules
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TargetHSP
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RecptorHSP
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Research Area——
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Indication——
Chemical Information
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CAS Number167782-17-4
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Formula Weight389.45
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Molecular FormulaC21H27NO6
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(OC)C(/C=C(C)/C=C/CC/C=C(C)/C([C@@]12C(NC(C)(O)[C@]1([H])O2)=O)=O)=C/C
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Chemical NameMethyl (2E,3E,5E,9E)-2-ethylidene-11-[(1R,5R)-4-hydroxy-4-methyl-2-oxo-6-oxa-3-azabicyclo[3.1.0]hexan-1-yl]-4,10-dimethyl-11-oxoundeca-3,5,9-trienoate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Kakeya H, et al. J Antibiot (Tokyo). 1995 Jul;48(7):733-5.
2. Nagumo Y, Bioorg Med Chem Lett. 2004 Sep 6;14(17):4425-9.
3. Nagumo Y, et al. Biochem J. 2005 May 1;387(Pt 3):835-40.
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