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Home - Products - Metabolic Enzyme/Protease - Retinoid Receptor - BMS641

BMS641

CAS No. 369364-50-1

BMS641( —— )

Catalog No. M34187 CAS No. 369364-50-1

BMS641 (BMS-209641) is a selective and potent RARβ agonist with high affinity for RARβ, which synergistically activates RARβ and RARgamma to induce cellular maturation into specialized neuronal subtypes.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 242 Get Quote
5MG 376 Get Quote
10MG 629 Get Quote
25MG 1178 Get Quote
50MG 1684 Get Quote
100MG 2223 Get Quote
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Biological Information

  • Product Name
    BMS641
  • Note
    Research use only, not for human use.
  • Brief Description
    BMS641 (BMS-209641) is a selective and potent RARβ agonist with high affinity for RARβ, which synergistically activates RARβ and RARgamma to induce cellular maturation into specialized neuronal subtypes.
  • Description
    BMS641 (BMS-209641) is a selective RARβ agonist. BMS641 has a higher affinity for RARβ (Kd, 2.5 nM) that is 100 times higher than that for RARα (Kd, 225 nM) or RARγ (Kd, 223 nM).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Retinoid Receptor
  • Recptor
    Retinoid Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    369364-50-1
  • Formula Weight
    414.92
  • Molecular Formula
    C27H23ClO2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 8.33 mg/mL (20.08 mM; Ultrasonic )
  • SMILES
    CC1(C)C=2C(C(=CC1)C3=CC=CC=C3)=CC(/C=C/C4=C(Cl)C=C(C(O)=O)C=C4)=CC2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Germain P, et al. Rational design of RAR-selective ligands revealed by RARbeta crystal stucture. EMBO Rep. 2004;5(9):877-882. ?
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