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PA452
CAS No. 457657-34-0
PA452( —— )
Catalog No. M26781 CAS No. 457657-34-0
PA452 is a retinoic X receptor (RXR) specific antagonist. PA452 suppresses the effect of Retinoic acid (RA) on Th1/Th2 development.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 274 | In Stock |
|
| 5MG | 250 | In Stock |
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| 10MG | 402 | In Stock |
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| 25MG | 657 | In Stock |
|
| 50MG | 917 | In Stock |
|
| 100MG | 1256 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamePA452
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NoteResearch use only, not for human use.
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Brief DescriptionPA452 is a retinoic X receptor (RXR) specific antagonist. PA452 suppresses the effect of Retinoic acid (RA) on Th1/Th2 development.
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DescriptionPA452 is a retinoic X receptor (RXR) specific antagonist. PA452 suppresses the effect of Retinoic acid (RA) on Th1/Th2 development.(In Vitro):PA452 suppresses the Troglitazone (TZ)-induced CK13 expression. In normal human urothelial (NHU) cells, PA452 (0.01-1 μM) inhibits retinoic X receptor.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetRetinoid Receptor
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RecptorDPPH
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Research Area——
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Indication——
Chemical Information
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CAS Number457657-34-0
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Formula Weight439.6
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Molecular FormulaC26H37N3O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 40 mg/mL (90.99 mM)
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SMILESCCCCCCOc1cc2c(cc1N(C)c1ncc(cn1)C(O)=O)C(C)(C)CCC2(C)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Cho MH, Paik YS, Hahn TR. Physical stability of shikonin derivatives from the roots of Lithospermum erythrorhizon cultivated in Korea. J Agric Food Chem. 1999 Oct;47(10):4117-20.
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