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GaTx2

GaTx2

Catalog No. M30682

Very high affinity ClC-2 blocker (apparent KD ~ 50 pM). Slows ClC-2 activation and inhibits slow-gating but does not inhibit open ClC-2 channels. Selective for ClC-2 over other ClC family members (ClC-0, ClC-1, ClC-3 and ClC-4), CFTR, GABAC, CaCC and KV1.2.

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Biological Information

  • Product Name
    GaTx2
  • Brief Description
  • Description
  • Storage
  • Note
    Research use only, not for human use.
  • Reference
    1. Schiffhauer et al (2013) Dual activation of CFTR and CLCN2 by lubipro. in murine nasal epithelia. Am.J.Physiol.Lung Cell Mol.Physiol. 304 L324 PMID:
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  • GaTx2

    Very high affinity ClC-2 blocker (apparent KD ~ 50 pM). Slows ClC-2 activation and inhibits slow-gating but does not inhibit open ClC-2 channels. Selective for ClC-2 over other ClC family members (ClC-0, ClC-1, ClC-3 and ClC-4), CFTR, GABAC, CaCC and KV1.2.

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