Zebularine

CAS No. 3690-10-6

Zebularine( —— )

Catalog No. M14269 CAS No. 3690-10-6

Zebularine is a DNA methylation inhibitor that forms a covalent complex with DNA methyltransferases, also inhibits cytidinedeaminase with Ki of 2 μM in a cell-free assay.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 34 In Stock
10MG 52 In Stock
25MG 114 In Stock
50MG 206 In Stock
100MG 267 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Zebularine
  • Note
    Research use only, not for human use.
  • Brief Description
    Zebularine is a DNA methylation inhibitor that forms a covalent complex with DNA methyltransferases, also inhibits cytidinedeaminase with Ki of 2 μM in a cell-free assay.
  • Description
    Zebularine is a DNA methylation inhibitor that forms a covalent complex with DNA methyltransferases, also inhibits cytidinedeaminase with Ki of 2 μM in a cell-free assay.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Chromatin/Epigenetic
  • Target
    DNMT
  • Recptor
    Cytidine deaminase
  • Research Area
    Cardiovascular Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    3690-10-6
  • Formula Weight
    228.2
  • Molecular Formula
    C9H12N2O5
  • Purity
    >98% (HPLC)
  • Solubility
    Water: 46 mg/mL (201.57 mM); DMSO: 46 mg/mL (201.57 mM)
  • SMILES
    C1=CN(C(=O)N=C1)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Zhou L, et al. J Mol Biol, 2002, 321(4), 591-599.
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  • Zebularine

    Zebularine is a DNA methylation inhibitor that forms a covalent complex with DNA methyltransferases, also inhibits cytidinedeaminase with Ki of 2 μM in a cell-free assay.