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XPW1
CAS No. 2700286-66-2
XPW1( —— )
Catalog No. M37124 CAS No. 2700286-66-2
XPW1 is a new potent and selective CDK9 inhibitor with antitumour activity that transcriptionally inhibits the DNA repair process in ccRCC cells.XPW1 can be used to study clear cell renal cell carcinoma.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 160 | Get Quote |
|
| 5MG | 246 | Get Quote |
|
| 10MG | 395 | Get Quote |
|
| 25MG | 766 | Get Quote |
|
| 50MG | 1030 | Get Quote |
|
| 100MG | 1341 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameXPW1
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NoteResearch use only, not for human use.
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Brief DescriptionXPW1 is a new potent and selective CDK9 inhibitor with antitumour activity that transcriptionally inhibits the DNA repair process in ccRCC cells.XPW1 can be used to study clear cell renal cell carcinoma.
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DescriptionXPW1 is a potent and selective CDK9 inhibitor with excellent activity against clear cell renal cell carcinoma (ccRCC) and low toxicity.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetCDK
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RecptorCDK
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Research Area——
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Indication——
Chemical Information
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CAS Number2700286-66-2
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Formula Weight656.19
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Molecular FormulaC36H39ClFN7O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 31.25 mg/mL (47.62 mM; Ultrasonic (<60°C)
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SMILESClC1=C(C=2N=C(NCC3=CC(F)=CC=C3)C=CC2)C=C(N[C@H]4CC[C@H](NC(=O)C5=CC=C(NC(/C=C/CN(C)C)=O)C=C5)CC4)N=C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Kuang Z, et al. The novel CDK9 inhibitor, XPW1, alone and in combination with BRD4 inhibitor JQ1, for the treatment of clear cell renal cell carcinoma. Br J Cancer. 2023 Oct 26.?
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