Vc-MMAD( —— )

Catalog No. M33562 CAS No. 1401963-17-4

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Vc-MMAD
Note

Research use only, not for human use.
Brief Description

Vc-MMAD, a drug-linker conjugate for Antibody-Drug Conjugates (ADCs), combines the ADC linker Val-Cit (Valine-Citrulline) with the potent tubulin inhibitor MMAD.
Description

Vc-MMAD consists the ADCs linker (Val-Cit) and potent tubulin inhibitor (MMAD). Vc-MMAD is a agent-linker conjugate for ADC.
In Vitro

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In Vivo

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Synonyms

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Pathway

Antibody Drug Conjugates (ADC)
Target

Drug-Linker Conjugates
Recptor

Drug-Linker Conjugates for ADC
Research Area

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Indication

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CAS Number

1401963-17-4
Formula Weight

1369.71
Molecular Formula

C70H104N12O14S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : ≥ 160 mg/mL (116.81 mM )
SMILES

CCC(C)C(C(CC(=O)N1CCCC1C(OC)C(C)C(=O)NC(Cc1ccccc1)c1nccs1)OC)N(C)C(=O)C(NC(=O)C(C(C)C)N(C)C(=O)OCc1ccc(NC(=O)C(CCCNC(N)=O)NC(=O)C(NC(=O)CCCCCN2C(=O)C=CC2=O)C(C)C)cc1)C(C)C
Chemical Name

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1. Antibody-drug conjugates Patent: WO 2013068874 A1

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