Val-Cit-PAB-MMAE( —— )

Catalog No. M15448 CAS No. 644981-35-1

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Product Name

Val-Cit-PAB-MMAE
Note

Research use only, not for human use.
Brief Description

A drug-linker conjugate for Antibody-drug conjugates (ADCs) by using the anti-mitotic agent, monomethyl auristatin E (MMAE), linked via the cleavable peptide Val-Cit-PAB.
Description

A drug-linker conjugate for Antibody-drug conjugates (ADCs) by using the anti-mitotic agent, monomethyl auristatin E (MMAE), linked via the cleavable peptide Val-Cit-PAB.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Antibody Drug Conjugates (ADC)
Target

Drug-Linker Conjugates
Recptor

Drug-Linker Conjugates
Research Area

Other Indications
Indication

——

CAS Number

644981-35-1
Formula Weight

1123.427
Molecular Formula

C58H94N10O12
Purity

>98% (HPLC)
Solubility

DMSO: 10 mM
SMILES

CCC(C)C(C(CC(=O)N1CCCC1C(C(C)C(=O)NC(C)C(C2=CC=CC=C2)O)OC)OC)N(C)C(=O)C(C(C)C)NC(=O)C(C(C)C)N(C)C(=O)OCC3=CC=C(C=C3)NC(=O)C(CCCNC(=O)N)NC(=O)C(C(C)C)N
Chemical Name

L-Valinamide, N-methyl-N-[[[4-[[L-valyl-N5-(aminocarbonyl)-L-ornithyl]amino]phenyl]methoxy]carbonyl]-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S