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UNC669
CAS No. 1314241-44-5
UNC669( —— )
Catalog No. M17941 CAS No. 1314241-44-5
UNC669 is an effective and specific MBT (malignant brain tumor) inhibitor with IC50 of 4.2/3.1 uM for L3MBTL1/3.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 43 | In Stock |
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| 25MG | 71 | In Stock |
|
| 50MG | 100 | In Stock |
|
| 100MG | 178 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameUNC669
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NoteResearch use only, not for human use.
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Brief DescriptionUNC669 is an effective and specific MBT (malignant brain tumor) inhibitor with IC50 of 4.2/3.1 uM for L3MBTL1/3.
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DescriptionUNC669 is an effective and specific MBT (malignant brain tumor) inhibitor with IC50 of 4.2/3.1 uM for L3MBTL1/3.
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In VitroL3MBTL1, a paralogue of Drosophila tumor suppressor lethal(3)malignant brain tumor (l(3)mbt), binds histones in a methylation state-dependent manner and contributes to higher order chromatin structure and transcriptional repression. Similar to L3MBTL1, the closely related protein, L3MBTL3, also contains three MBT repeats and has been shown to play a role in meduloblastoma formation and normal hematopoiesis in humans.
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In Vivo——
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Synonyms——
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PathwayAutophagy
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TargetAutophagy
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RecptorL3MBTL1| L3MBTL3| L3MBTL4
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Research AreaOthers-Field
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Indication——
Chemical Information
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CAS Number1314241-44-5
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Formula Weight338.24
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Molecular FormulaC15H20BrN3O
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Purity>98% (HPLC)
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SolubilityDMSO : 50 mg/mL 147.82 mM;
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SMILESc1c(cncc1Br)C(=O)N1CCC(CC1)N1CCCC1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Herold JM, et al. J Med Chem. 2011, 54(7), 2504-2511.
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