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ULK-101
CAS No. 2443816-45-1
ULK-101( —— )
Catalog No. M24125 CAS No. 2443816-45-1
ULK-101 suppresses autophagy induction and autophagic flux in response to different stimuli.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 264 | In Stock |
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| 2MG | 152 | In Stock |
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| 5MG | 261 | In Stock |
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| 10MG | 410 | In Stock |
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| 25MG | 696 | In Stock |
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| 50MG | 949 | In Stock |
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| 100MG | 1302 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameULK-101
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NoteResearch use only, not for human use.
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Brief DescriptionULK-101 suppresses autophagy induction and autophagic flux in response to different stimuli.
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DescriptionULK-101 suppresses autophagy induction and autophagic flux in response to different stimuli.
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In VitroULK-101 (0-5 μM) reduces BafA1-induced LC3B-II accumulation in U2OS cells in a concentration-dependent manner.
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In Vivo——
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Synonyms——
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PathwayAutophagy
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TargetAutophagy
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RecptorULK1
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Research Area——
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Indication——
Chemical Information
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CAS Number2443816-45-1
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Formula Weight460.4
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Molecular FormulaC22H16F4N4OS
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Purity>98% (HPLC)
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SolubilityDMSO:84mg/mL (182.43mM)
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SMILESO=C(C1=CC(C2=C3N=CC(C4=CC=C(F)C=C4)=CN3N=C2)=CS1)N[C@@H](C5CC5)C(F)(F)F
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Martin KR, Celano SL, Solitro AR, et al. A Potent and Selective ULK1 Inhibitor Suppresses Autophagy and Sensitizes Cancer Cells to Nutrient Stress. iScience. 2018;8:74-84. doi:10.1016/j.isci.2018.09.012
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