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ULK-101
CAS No. 2443816-45-1
ULK-101( —— )
Catalog No. M24125 CAS No. 2443816-45-1
ULK-101 suppresses autophagy induction and autophagic flux in response to different stimuli.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 218 | In Stock |
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| 5MG | 335 | In Stock |
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| 10MG | 537 | In Stock |
|
| 25MG | 842 | In Stock |
|
| 50MG | 1134 | In Stock |
|
| 100MG | 1521 | In Stock |
|
| 500MG | 3042 | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameULK-101
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NoteResearch use only, not for human use.
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Brief DescriptionULK-101 suppresses autophagy induction and autophagic flux in response to different stimuli.
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DescriptionULK-101 suppresses autophagy induction and autophagic flux in response to different stimuli.
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In VitroULK-101 (0-5 μM) reduces BafA1-induced LC3B-II accumulation in U2OS cells in a concentration-dependent manner.
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In Vivo——
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Synonyms——
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PathwayAutophagy
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TargetAutophagy
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RecptorULK1
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Research Area——
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Indication——
Chemical Information
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CAS Number2443816-45-1
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Formula Weight460.4
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Molecular FormulaC22H16F4N4OS
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Purity>98% (HPLC)
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SolubilityDMSO:84mg/mL (182.43mM)
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SMILESO=C(C1=CC(C2=C3N=CC(C4=CC=C(F)C=C4)=CN3N=C2)=CS1)N[C@@H](C5CC5)C(F)(F)F
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Gemcitabine (elaidat...
Gemcitabine elaidate, is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with potential antineoplastic activity.?
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LYN-1604 2HCl 221675...
LYN-1604 is a novel ULK1 activator.It inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.?LYN-1604, to be the best candidate for a ULK1 agonist.?LYN-1604 induced cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.?LYN-1604 has potential for good therapeutic effects on TNBC by targeting ULK1-modulated cell death in vivo.
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Sulfuretin
Sulfuretin is a potent anti-oxidant, has protective effect against t-BHP-induced oxidative damage in human liver-derived HepG2 cells is attributable to its ability to scavenge ROS and up-regulate the activity of HO-1 through the Nrf2/ARE and JNK/ERK signaling pathways.
