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UCB-5307
CAS No. 1515887-44-1
UCB-5307( —— )
Catalog No. M35511 CAS No. 1515887-44-1
UCB-5307 is a small molecule compound that inhibits TNFR1 signal transduction and downstream function in vitro.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 78 | In Stock |
|
| 5MG | 116 | In Stock |
|
| 10MG | 188 | In Stock |
|
| 25MG | 415 | In Stock |
|
| 50MG | 610 | In Stock |
|
| 100MG | 851 | In Stock |
|
| 500MG | 1692 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameUCB-5307
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NoteResearch use only, not for human use.
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Brief DescriptionUCB-5307 is a small molecule compound that inhibits TNFR1 signal transduction and downstream function in vitro.
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DescriptionUCB-5307 is a potent TNF signaling inhibitor with a KD of 9 nM for human TNFα. UCB-5307 can penetrate the preformed hTNF/hTNFR1 complex.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayApoptosis
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TargetTNF
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RecptorTNF
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Research Area——
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Indication——
Chemical Information
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CAS Number1515887-44-1
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Formula Weight343.42
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Molecular FormulaC22H21N3O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (145.59 mM; Ultrasonic )
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SMILESCc1ccc(C)c(Cn2c(nc3ccccc23)C(O)c2ccncc2)c1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. O'Connell J, et al. Small molecules that inhibit TNF signalling by stabilising an asymmetric form of the trimer. Nat Commun. 2019 Dec 19;10(1):5795.?
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