Tris(4-aminophenyl)methane

CAS No. 548-61-8

Tris(4-aminophenyl)methane( Leucopararosaniline )

Catalog No. M24535 CAS No. 548-61-8

Tris(4-aminophenyl)methane, a triphenylmethane dye, is a weak HCV helicase inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
100MG 38 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Tris(4-aminophenyl)methane
  • Note
    Research use only, not for human use.
  • Brief Description
    Tris(4-aminophenyl)methane, a triphenylmethane dye, is a weak HCV helicase inhibitor.
  • Description
    Tris(4-aminophenyl)methane, a triphenylmethane dye, is a weak HCV helicase inhibitor.
  • In Vitro
    Tris(4-aminophenyl)methane (Compound 8) shows weak HCV helicase inhibition (30% inhibition at 100 μM). To preserve RNA in a biological sample for analysis, the sample is incubated with an RNA preservative capable of precipitating RNA in an aqueous solution, such as a triphenylmethane dye (e.g., methyl green, crystal violet, pararosaniline, or Tris(4-aminophenyl)methane), cresyl violet, or cobalt ions. RNA preservation may be used in an immunostaining assay and other histochemical methods.
  • In Vivo
    ——
  • Synonyms
    Leucopararosaniline
  • Pathway
    Microbiology/Virology
  • Target
    HCV
  • Recptor
    HCV helicase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    548-61-8
  • Formula Weight
    289.37
  • Molecular Formula
    C19H19N3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (172.79 mM)
  • SMILES
    Nc1ccc(C(c(cc2)ccc2N)c(cc2)ccc2N)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Chen CS, et al. Structure-based discovery of triphenylmethane derivatives as inhibitors of hepatitis C virushelicase. J Med Chem. 2009 May 14;52(9):2716-23.
molnova catalog
related products
  • BLT-1

    BLT-1 is a scavenger receptor BI (SR-BI)inhibitor.BLT-1 has IC50s of 60 and 110 nM for cellular DiI-HDL and [3H]CE-HDL uptake in ldlA[mSR-BI] cells.

  • MK-3281

    MK-3281 is a potent and orally bioavailable inhibitor of HCV NS5B polymerase with IC50 of 6 nM; MK-3281 is an equally potent inhibitor of gt 1a (EC50=28 nM), 1b BK (EC50=9 nM), and 3a (EC50=37 nM) replicons.

  • Coblopasvir

    Coblopasvir (KW136, KW-136) is a novel HCV NS5A inhibitor under development for treatment of HCV infection.