BLT-1

CAS No. 321673-30-7

BLT-1( —— )

Catalog No. M22568 CAS No. 321673-30-7

BLT-1 is a scavenger receptor BI (SR-BI)inhibitor.BLT-1 has IC50s of 60 and 110 nM for cellular DiI-HDL and [3H]CE-HDL uptake in ldlA[mSR-BI] cells.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 49 In Stock
5MG 80 In Stock
10MG 147 In Stock
25MG 258 In Stock
50MG 410 In Stock
100MG 591 In Stock
200MG Get Quote In Stock
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1G Get Quote In Stock

Biological Information

  • Product Name
    BLT-1
  • Note
    Research use only, not for human use.
  • Brief Description
    BLT-1 is a scavenger receptor BI (SR-BI)inhibitor.BLT-1 has IC50s of 60 and 110 nM for cellular DiI-HDL and [3H]CE-HDL uptake in ldlA[mSR-BI] cells.
  • Description
    BLT-1 is a scavenger receptor BI (SR-BI)inhibitor.BLT-1 has IC50s of 60 and 110 nM for cellular DiI-HDL and [3H]CE-HDL uptake in ldlA[mSR-BI] cells. BLT-1 can inhibit SR-BI-dependent selective uptake of [3H]CE from [3H]CE-HDL by mSR-BI-t1-containing liposomes in cells (IC50=0.057 μM) and liposomes (IC50=0.098 μM). BLT-1 (50 μM; 3 hours) does not induce general defects in clathrin-dependent and -independent intracellular membrane trafficking in HeLa, BSC-1 cells.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Microbiology/Virology
  • Target
    HCV
  • Recptor
    HCV|SR-BI
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    321673-30-7
  • Formula Weight
    241.4
  • Molecular Formula
    C12H23N3S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:38.67 mg/mL (160.19mM; Need ultrasonic)
  • SMILES
    CCCCCCC1CCCC1=NNC(N)=S
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Nieland TJ, et al. Discovery of chemical inhibitors of the selective transfer of lipids mediated by the HDL receptorSR-BI. Proc Natl Acad Sci U S A. 2002 Nov 26;99(24):15422-7.
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