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TriGalNAc CBz

CAS No. 186613-57-0

TriGalNAc CBz( —— )

Catalog No. M37133 CAS No. 186613-57-0

TriGalNAc CBz is a GalNAc derivative. As an ASGPR ligand, tri-GalNAc targets lysosomes in mRNA drug delivery and LYTAC studies.L-DABA hydrobromide.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    TriGalNAc CBz
  • Note
    Research use only, not for human use.
  • Brief Description
    TriGalNAc CBz is a GalNAc derivative. As an ASGPR ligand, tri-GalNAc targets lysosomes in mRNA drug delivery and LYTAC studies.L-DABA hydrobromide.
  • Description
    TriGalNAc CBz is a GalNAc derivative and tri-GalNAc is an asialoglycoprotein receptor (ASGPR) ligand. TriGalNAc CBz can be used for mRNA drug delivery as well as lysosomal targeted chimerism (LYTAC) studies.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    LYTACs
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    186613-57-0
  • Formula Weight
    633.64
  • Molecular Formula
    C34H35NO11
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (157.82 mM; Ultrasonic (<60°C)
  • SMILES
    O(C(=O)C1=CC=CC=C1)[C@H]2[C@@H](OC(=O)C3=CC=CC=C3)[C@@H](COC(=O)C4=CC=CC=C4)O[C@@H](OCCCCC(O)=O)[C@@H]2NC(C)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kallanthottathil G. Rajeev, et al. Compositions and methods for targeted rna delivery. WO2021178725.
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