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Home - Products - Metabolic Enzyme/Protease - Aminopeptidase - SC-22716

SC-22716

CAS No. 262451-89-8

SC-22716( —— )

Catalog No. M34414 CAS No. 262451-89-8

SC-22716 is an orally active leukotriene A4 (LTA4) hydrolase inhibitor.SC-22716 has potential anti-inflammatory activity and may be used in the study of inflammatory bowel disease and psoriasis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    SC-22716
  • Note
    Research use only, not for human use.
  • Brief Description
    SC-22716 is an orally active leukotriene A4 (LTA4) hydrolase inhibitor.SC-22716 has potential anti-inflammatory activity and may be used in the study of inflammatory bowel disease and psoriasis.
  • Description
    SC-22716 is a potent, competitive, reversible inhibitor of human LTA4 hydrolase, with an IC50 of 0.20 μM. SC-22716 has potential for the research of inflammatory bowel disease (IBD) and psoriasis.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Aminopeptidase
  • Recptor
    Aminopeptidase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    262451-89-8
  • Formula Weight
    267.37
  • Molecular Formula
    C18H21NO
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O(C=1C=CC(=CC1)C=2C=CC=CC2)CCN3CCCC3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Penning TD, et, al. Structure-activity relationship studies on 1-[2-(4-Phenylphenoxy)ethyl]pyrrolidine (SC-22716), a potent inhibitor of leukotriene A(4) (LTA(4)) hydrolase. J Med Chem. 2000 Feb 24;43(4):721-35.?
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