NNGH

CAS No. 161314-17-6

NNGH( —— )

Catalog No. M33755 CAS No. 161314-17-6

NNGH is a matrix metalloproteinase 3 (MMP-3) inhibitor with anticancer activity that counteracts the inhibitory effects of E2 and DHT on RANKL membrane binding.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    NNGH
  • Note
    Research use only, not for human use.
  • Brief Description
    NNGH is a matrix metalloproteinase 3 (MMP-3) inhibitor with anticancer activity that counteracts the inhibitory effects of E2 and DHT on RANKL membrane binding.
  • Description
    NNGH is a stromelysin-1 (MMP-3) inhibitor. MMP-3 is both a direct transcriptional target and a necessary contributor of the Wnt/β-catenin signaling pathway. Matrix metalloproteinases (MMPs) play a well-defined role in later stages of tumor progression.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    MMP
  • Recptor
    MMP
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    161314-17-6
  • Formula Weight
    316.37
  • Molecular Formula
    C13H20N2O5S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(NO)CN(CC(C)C)S(=O)(=O)C1=CC=C(OC)C=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Laurence Blavier, et al. Stromelysin-1 (MMP-3) is a target and a regulator of Wnt1-induced epithelial-mesenchymal transition (EMT). Cancer Biol Ther. 2010 Jul 15;10(2):198-208.?
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