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Moracin C

CAS No. 69120-06-5

Moracin C( —— )

Catalog No. M37739 CAS No. 69120-06-5

Moracin C, a natural compound found in Morus mesozygia, Morus alba var. multicaulis, is an anti-inflammatory agent.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Moracin C
  • Note
    Research use only, not for human use.
  • Brief Description
    Moracin C, a natural compound found in Morus mesozygia, Morus alba var. multicaulis, is an anti-inflammatory agent.
  • Description
    Moracin C, a natural product, is an anti-inflammatory agent. Moracin C inhibits LPS-activated reactive oxygen species (ROS) and nitric oxide (NO) release from cells.
  • In Vitro
    RT-PCR Cell Line:RAW 264.7 macrophages Concentration:1, 10, 25, 50 μM Incubation Time:2 h Result:Inhibited LPS-induced mRNA expression of iNOS and COX-2.Western Blot Analysis Cell Line:RAW 264.7 macrophages Concentration:1, 10, 25, 50 μM Incubation Time:2 h Result:Inhibited LPS-induced TLR4 expression and NF-κB activation.Reduced phosphorylated p38, ERK and JNK levels.
  • In Vivo
    Animal Model:Mice (PK Assay)Dosage:100 mg/kg Administration:Oral gavage Result:Pharmacokinetic profile of Moracin C.
  • Synonyms
    ——
  • Pathway
    Immunology/Inflammation
  • Target
    ROS
  • Recptor
    ROS | NO Synthase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    69120-06-5
  • Formula Weight
    310.34
  • Molecular Formula
    C19H18O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (805.57 mM; Ultrasonic )
  • SMILES
    CC(C)=CCc1c(O)cc(cc1O)-c1cc2ccc(O)cc2o1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Yao X, et al. Moracin C, A Phenolic Compound Isolated from Artocarpus heterophyllus, Suppresses Lipopolysaccharide-Activated Inflammatory Responses in Murine Raw264.7 Macrophages. Int J Mol Sci. 2016 Jul 25;17(8):1199. ?
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