Magnoflorine
CAS No. 2141-09-5
Magnoflorine( Magnoflorine | α-Magnoflorine | Thalictrine )
Catalog No. M17720 CAS No. 2141-09-5
Sinomeni Caulis et Rhizoma has sedative and anxiolytic effects, probably mediated by Magnoflorine through a GABAergic mechanism of action.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | 261 | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameMagnoflorine
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NoteResearch use only, not for human use.
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Brief DescriptionSinomeni Caulis et Rhizoma has sedative and anxiolytic effects, probably mediated by Magnoflorine through a GABAergic mechanism of action.
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DescriptionSinomeni Caulis et Rhizoma has sedative and anxiolytic effects, probably mediated by Magnoflorine through a GABAergic mechanism of action. Magnoflorine and Sinomenine have protective effects, are mediated by some mechanism other than prevention of micelle formation or protection of the erythrocyte membrane against osmotic imbalance.
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In Vitro——
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In Vivo——
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SynonymsMagnoflorine | α-Magnoflorine | Thalictrine
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PathwayCell Cycle/DNA Damage
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Targetc-Myc
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RecptorOthers
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Research AreaOthers-Field
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Indication——
Chemical Information
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CAS Number2141-09-5
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Formula Weight342.41
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Molecular FormulaC20H24NO4+
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Purity>98% (HPLC)
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Solubility——
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SMILESC[N+]1(CCC2=CC(=C(C3=C2C1CC4=C3C(=C(C=C4)OC)O)O)OC)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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IRES-C11
A novel, spectfic c-Myc IRES (internal ribosome entry site) function inhibitor that prevents binding of hnRNP A1 to the Myc IRES and specifically inhibits Myc IRES activity in MM cells.
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APTO-253
APTO-253 inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells. APTO-253 mediates anticancer activity through the induction of the KLF4 tumor suppressor.APTO-253 (5 μM) induces KLF4 expression and enhances apoptosis induced by NSC 119875 in both SKOV3 and OVCAR3 cells.
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Stauprimide
A staurosporine analog that promotes embryonic stem cell (ESC) differentiation by inhibiting nuclear localization of the MYC transcription factor NME2.
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