Stauprimide
CAS No. 154589-96-5?
Stauprimide( N-Benzoyl-7-oxo Staurosporine )
Catalog No. M12193 CAS No. 154589-96-5?
A staurosporine analog that promotes embryonic stem cell (ESC) differentiation by inhibiting nuclear localization of the MYC transcription factor NME2.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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| 100MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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Biological Information
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Product NameStauprimide
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NoteResearch use only, not for human use.
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Brief DescriptionA staurosporine analog that promotes embryonic stem cell (ESC) differentiation by inhibiting nuclear localization of the MYC transcription factor NME2.
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DescriptionA staurosporine analog that promotes embryonic stem cell (ESC) differentiation by inhibiting nuclear localization of the MYC transcription factor NME2, which in turn results in down-regulation of MYC transcription; increases the efficiency of mouse and human embryonic stem cell differentiation in conjunction with lineage specification cues with EC50 of 0.3 uM.
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In Vitro——
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In Vivo——
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SynonymsN-Benzoyl-7-oxo Staurosporine
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PathwayCell Cycle/DNA Damage
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Targetc-Myc
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Recptorc-Myc
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Research Area——
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Indication——
Chemical Information
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CAS Number154589-96-5?
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Formula Weight584.6
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Molecular FormulaC35H28N4O5
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Purity>98% (HPLC)
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Solubility——
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SMILESCC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)C(=O)NC6=O)N(C)C(=O)C9=CC=CC=C9)OC
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Chemical NameN-((5R,7R,8R,9S)-8-methoxy-9-methyl-14,16-dioxo-6,7,8,9,15,16-hexahydro-5H,14H-17-oxa-4b,9a,15-triaza-5,9-methanodibenzo[b,h]cyclonona[jkl]cyclopenta[e]-as-indacen-7-yl)-N-methylbenzamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Bouvard C, et al. Proc Natl Acad Sci U S A. 2017 Mar 28;114(13):3497-3502.
2. Zhu S, et al. Cell Stem Cell. 2009 May 8;4(5):416-26.
3. Tahamtani Y, et al. Stem Cells Dev. 2013 May 1;22(9):1419-32.
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