Ciwujianoside C3

CAS No. 114906-74-0

Ciwujianoside C3( ——— )

Catalog No. M38898 CAS No. 114906-74-0

Ciwujianoside C3, an orally active and brain penetrated compound, is isolated the leaves of Acanthopanax henryi Harms. Ciwujianoside C3 has anti-inflammatory effect and can reinforces object recognition memory.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Ciwujianoside C3
  • Note
    Research use only, not for human use.
  • Brief Description
    Ciwujianoside C3, an orally active and brain penetrated compound, is isolated the leaves of Acanthopanax henryi Harms. Ciwujianoside C3 has anti-inflammatory effect and can reinforces object recognition memory.
  • Description
    Ciwujianoside C3 comes from Acanthopanax senticosus.
  • In Vitro
    Cell Viability Assay Cell Line:RAW?264.7 cells Concentration:10 μM, 20 μM and 40?μM Incubation Time:24 hours Result:Has no effect on cell cytotoxicity and inhibits NO production Western Blot Analysis Cell Line:RAW?264.7 cells Concentration:10 μM, 20 μM and 40?μM Incubation Time:24 hours Result:Decreases p-ERK and p-JNK expression. RT-PCR Cell Line:RAW?264.7 cells Concentration:10 μM, 20 μM and 40?μM Incubation Time:24 hours Result:Decreased COX-2 and iNOS mRNA expression in a dose-dependent manner.
  • In Vivo
    Animal Model:Mice Dosage:0.5 mg/kg Administration:Oral administration; 0.5 mg/kg/day; 17 days Result:Reinforced object recognition memory.
  • Synonyms
    ———
  • Pathway
    Immunology/Inflammation
  • Target
    NOS
  • Recptor
    NO Synthase
  • Research Area
    ———
  • Indication
    ———

Chemical Information

  • CAS Number
    114906-74-0
  • Formula Weight
    1059.25
  • Molecular Formula
    C53H86O21
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 50 mg/mL (47.20 mM; ultraphonic; )
  • SMILES
    ———
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kang DH, et al. Anti-inflammatory effects of Ciwujianoside C3, extracted from the leaves of Acanthopanax henryi (Oliv.) Harms, on LPS-stimulated RAW 264.7 cells. Mol Med Rep. 2016 Oct;14(4):3749-58.?
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