Wilfortrine

CAS No. 37239-48-8

Wilfortrine( ——— )

Catalog No. M38649 CAS No. 37239-48-8

Wilfortrine is a bioactive sesquiterpene alkaloid. Wilfortrine exhibits immunosuppresive effects. Wilfortrine also can inhibit leukaemia cell growth in mice and shows anti-HIV activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Wilfortrine
  • Note
    Research use only, not for human use.
  • Brief Description
    Wilfortrine is a bioactive sesquiterpene alkaloid. Wilfortrine exhibits immunosuppresive effects. Wilfortrine also can inhibit leukaemia cell growth in mice and shows anti-HIV activity.
  • Description
    Wilfortrine can induce liver cancer cell HepG2 apoptosis, but with no effect on the cell cycle, mainly by promoting Bax expression and inhibiting anti-apoptotic protein Bcl-2 expression.
  • In Vitro
    ———
  • In Vivo
    ———
  • Synonyms
    ———
  • Pathway
    Angiogenesis
  • Target
    Bcl-2
  • Recptor
    Bcl-2;Immunology & Inflammation related
  • Research Area
    ———
  • Indication
    ———

Chemical Information

  • CAS Number
    37239-48-8
  • Formula Weight
    873.814
  • Molecular Formula
    C41H47NO20
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 50 mg/mL (57.22 mM)
  • SMILES
    ———
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Ouyang XK, et, al. Simultaneous determination of four sesquiterpene alkaloids in Tripterygium wilfordii Hook. F. extracts by high-performance liquid chromatography. Phytochem Anal. Jul-Aug 2007;18(4):320-5.?
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