SW076956( SW-076956 )

Catalog No. M16188 CAS No. 851717-83-4

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

SW076956
Note

Research use only, not for human use.
Brief Description

SW076956 is a small molecule that selectively disrupt Beclin 1/Bcl-2 binding as compared to Bax/Bcl-2 and Bim/Bcl-2 binding and induces autophagic flux at concentrations with minimal cytotoxicity.
Description

SW076956 is a small molecule that selectively disrupt Beclin 1/Bcl-2 binding as compared to Bax/Bcl-2 and Bim/Bcl-2 binding and induces autophagic flux at concentrations with minimal cytotoxicity.
In Vitro

——
In Vivo

——
Synonyms

SW-076956
Pathway

Angiogenesis
Target

Bcl-2
Recptor

Bcl-2
Research Area

——
Indication

——

CAS Number

851717-83-4
Formula Weight

423.487
Molecular Formula

C22H21N3O4S
Purity

>98% (HPLC)
Solubility

——
SMILES

CC1=CC=C(C=C1)C(=O)N2C(CC(=N2)C3=CC=C(C=C3)NS(=O)(=O)C)C4=CC=CO4
Chemical Name

N-(4-(5-(furan-2-yl)-1-(4-methylbenzoyl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide

1. Chiang WC, et al. ACS Chem Biol. 2018 Jun 21. doi: 10.1021/acschembio.8b00421.

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