RH01386 is a small molecule that can prevent ER stress-induced β cell dysfunction and death, and inhibits proapoptotic gene expression,has the potential for type 2 diabetes treatment. RH01386 restores ER stress-impaired glucose-stimulated insulin secretion responses.

Dehydrocostus Lactone is a major sesquiterpene lactone isolated from the roots of Saussurea lappa.

Thymidine-5'-monophosphate (TMP) is found in DNA. In mammalian cells thymidine deprivation induces chromosome aberrations such as chromatid breaks chromatid interchanges and chromosome fragmentation.