PP5-IN-1

CAS No. 1022417-69-1

PP5-IN-1( —— )

Catalog No. M37297 CAS No. 1022417-69-1

PP5-IN-1 is a potent and competitive serine/threonine protein phosphatase-5 (PP5) inhibitor with potential anticancer activity that induces apoptosis in cancer cells.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 151 In Stock
10MG 242 In Stock
25MG 454 In Stock
50MG 710 In Stock
100MG 1097 In Stock
200MG Get Quote In Stock
500MG 2223 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    PP5-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    PP5-IN-1 is a potent and competitive serine/threonine protein phosphatase-5 (PP5) inhibitor with potential anticancer activity that induces apoptosis in cancer cells.
  • Description
    PP5-IN-1 (Compound P053) is a competitive inhibitor of Serine/threonine protein phosphatase-5 (PP5) that binds to its catalytic domain and causes apoptosis in renal cancer.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Phosphatase
  • Recptor
    Phosphatase | Apoptosis
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1022417-69-1
  • Formula Weight
    342.41
  • Molecular Formula
    C18H18N2O3S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (292.05 mM; Ultrasonic )
  • SMILES
    O=S(=O)(NC1=CC=C(C=C1)CC=2C=CC=CC2)C=3C(=NOC3C)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Elham F Ahanin, et al. Catalytic inhibitor of Protein Phosphatase 5 activates the extrinsic apoptotic pathway by disrupting complex II in kidney cancer. Cell Chem Biol. 2023 Oct 19;30(10):1223-1234.e12.?
molnova catalog
related products
  • GNF362

    GNF362 is an orally available, selective and potent inhibitor of inositol trisphosphate 3'kinase B (ITPKB), inhibits Itpka and Itpkc, overcomes TMZ chemoresistance, and selectively deletes donor allogeneic reactive T-cells.

  • Voclosporin

    Voclosporin (ISAtx-247) is a novel, orally available calcium-modulated phosphatase (CN; PP2B) inhibitor and immunosuppressant used for treating lupus nephritis.

  • JAB-3068

    JAB-3068 (SHP2-IN-6) is a potent SHP2 inhibitor exhibiting anticancer and antitumor properties, designed for research in breast, lung, and esophageal cancers.