h-NTPDase8-IN-1( —— )

Catalog No. M37238 CAS No. 716358-51-9

h-NTPDase8-IN-1 is a specific aminosulfonylbenzamide inhibitor of h-NTPDases8 (IC 50 = 0.28 ± 0.07 μM). h-NTPDase8-IN-1 can be used to study diseases brought about by aberrant h -NTPDase expression.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

h-NTPDase8-IN-1
Note

Research use only, not for human use.
Brief Description

h-NTPDase8-IN-1 is a specific aminosulfonylbenzamide inhibitor of h-NTPDases8 (IC 50 = 0.28 ± 0.07 μM). h-NTPDase8-IN-1 can be used to study diseases brought about by aberrant h -NTPDase expression.
Description

h-NTPDase8-IN-1 (compound 2d) is a sulfamoyl-benzamides based and selective inhibitor for h-NTPDases8 (IC50=0.28 μM). h-NTPDases8 is involved in a variety of physiological and pathological functions，such as thrombosis，diabetes，inflammation，and cancer.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Metabolic Enzyme/Protease
Target

Phosphatase
Recptor

Phosphatase
Research Area

——
Indication

——

Chemical Information

CAS Number

716358-51-9
Formula Weight

275.71
Molecular Formula

C10H10ClNO4S
Purity

>98% (HPLC)
Solubility

——
SMILES

O=C(O)C1=CC(=CC=C1Cl)S(=O)(=O)NC2CC2
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Zaigham ZH, et al. Synthesis and biological evaluation of sulfamoyl benzamide derivatives as selective inhibitors for?h-NTPDases. RSC Adv. 2023 Jul 11;13(30):20909-20915.?

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