h-NTPDase-IN-4

CAS No. 2939933-09-0

h-NTPDase-IN-4( —— )

Catalog No. M37029 CAS No. 2939933-09-0

h-NTPDase-IN-4 is a pan-inhibitor of NTPDase, which can inhibit h-NTPDase1, 1h-NTPDase2, h-NTPDase3, h-NTPDase8. The IC50 values were 3.58 μM, 10.21 μM, 0.13 μM and 13.57 μM, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 93 Get Quote
5MG 140 Get Quote
10MG 224 Get Quote
25MG 435 Get Quote
50MG 696 Get Quote
100MG 888 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    h-NTPDase-IN-4
  • Note
    Research use only, not for human use.
  • Brief Description
    h-NTPDase-IN-4 is a pan-inhibitor of NTPDase, which can inhibit h-NTPDase1, 1h-NTPDase2, h-NTPDase3, h-NTPDase8. The IC50 values were 3.58 μM, 10.21 μM, 0.13 μM and 13.57 μM, respectively.
  • Description
    h-NTPDase-IN-4 (compound 4c) is a pan-inhibitor of NTPDase with IC50s of 3.58 μM (h-NTPDase1), 10.21 μM (h-NTPDase2), 0.13 μM (h-NTPDase3), 13.57 μM (h- NTPDase8).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Phosphatase
  • Recptor
    Phosphatase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2939933-09-0
  • Formula Weight
    560.36
  • Molecular Formula
    C22H8F12N2S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMF : 100 mg/mL (178.46 mM; Ultrasonic)
  • SMILES
    C(F)(F)(F)C=1C=C(C2=C3C(C(=CS3)C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)=NC=N2)C=C(C(F)(F)F)C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Zaman G, Ullah S, Uzair M, et al. Synthesis of Thieno [3, 2‐d] pyrimidine Derivatives through Sequential SNAr and Suzuki Reactions as Selective h‐NTPDases Inhibitors[J]. ChemMedChem, 2023: e202300165.
molnova catalog
related products
  • TCS 401

    TCS 401 is a selective inhibitor of protein-tyrosine phosphatase 1B (PTP1B; Ki = 0.29 μM).

  • Talabostat mesylate

    Talabostat mesylate is an orally active, selective inhibitor of dipeptidyl peptidases IV (DPP4, IC50: 0.18 nM), including tumor-associated fibroblast activation protein.

  • PTP1B-IN-22

    PTP1B-IN-22 is a protein tyrosine phosphatase 1B (PTP1B) inhibitor that inhibits glucose uptake in skeletal muscle L6 myotubes.