Cart
sales@molnova.com
17β-HSD10-IN-1
CAS No. 2316765-78-1
17β-HSD10-IN-1( —— )
Catalog No. M36963 CAS No. 2316765-78-1
17β-HSD10-IN-1 is an orally available 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10) inhibitor with blood-brain permeability and potency for the study of Alzheimer's disease.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 36 | In Stock |
|
| 5MG | 57 | In Stock |
|
| 10MG | 93 | In Stock |
|
| 25MG | 187 | In Stock |
|
| 50MG | 296 | In Stock |
|
| 100MG | 462 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 1014 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product Name17β-HSD10-IN-1
-
NoteResearch use only, not for human use.
-
Brief Description17β-HSD10-IN-1 is an orally available 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10) inhibitor with blood-brain permeability and potency for the study of Alzheimer's disease.
-
Description17β-HSD10-IN-1 (compound 9) is an orally active inhibitor of 17β-hydroxysteroid dehydrogenase type 10 (17β-HSD10) with blood-brain permeability. 17β-HSD10-IN-1 doesn't result additional effects for mitochondrial off-targets and cytotoxic or neurotoxic effects.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayMetabolic Enzyme/Protease
-
TargetDehydrogenase
-
RecptorDehydrogenase | Endogenous Metabolite
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2316765-78-1
-
Formula Weight376.82
-
Molecular FormulaC16H13ClN4O3S
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 25 mg/mL (66.34 mM; Ultrasonic )
-
SMILESO=C(NC1=NC=2C=CC(=CC2S1)NC(=O)C)NC3=CC=C(O)C(Cl)=C3
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Benek O, et al. Development of submicromolar 17尾-HSD10 inhibitors and their in vitro and in vivo evaluation. Eur J Med Chem. 2023 Oct 5;258:115593.聽?
molnova catalog
related products
-
Mycophenolate mofeti...
Mycophenolate mofetil is the 2-morpholinoethyl ester of mycophenolic acid (MPA), an immunosuppressive agent, inosine monophosphate dehydrogenase (IMPDH) inhibitor.
-
Methotrexate disodiu...
Methotrexate disodium is an tetrahydrofolate dehydrogenase inhibitor.
-
BI?3231
BI?3231 is a selective and potent inhibitor of hydroxysteroid 17?-dehydrogenase 13 HSD17B13, inhibiting hHSD17B13 and mHSD17B13.BI-3231 can be used for the study of alcohol-associated liver injury, fibrosis and cirrhosis.
