Cart
sales@molnova.com
AXC-715 trihydrochloride
CAS No. 2479276-17-8
AXC-715 trihydrochloride( —— )
Catalog No. M36450 CAS No. 2479276-17-8
AXC-715 trihydrochloride (T785 trihydrochloride) is a TLR7/TLR8 dual agonist for the synthesis of antibody-adjuvanted immunocouplings.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 208 | In Stock |
|
| 10MG | 341 | In Stock |
|
| 25MG | 554 | In Stock |
|
| 50MG | 749 | In Stock |
|
| 100MG | 1004 | In Stock |
|
| 200MG | 1358 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameAXC-715 trihydrochloride
-
NoteResearch use only, not for human use.
-
Brief DescriptionAXC-715 trihydrochloride (T785 trihydrochloride) is a TLR7/TLR8 dual agonist for the synthesis of antibody-adjuvanted immunocouplings.
-
DescriptionAXC-715 (T785) trihydrochloride is a TLR7/TLR8 dual agonist, extracted from patent WO2020168017 A1. AXC-715 trihydrochloride, compound D from WO2020190734A1, can be used for synthesis of antibody-adjuvant immunoconjugates, comprising an antibody construct that binds programmed death-ligand 1 (PD-L1) linked to one or more adjuvants.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayImmunology/Inflammation
-
TargetTLR
-
RecptorTLR
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2479276-17-8
-
Formula Weight420.81
-
Molecular FormulaC18H28Cl3N5
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 125 mg/mL (297.05 mM; Ultrasonic )
-
SMILESNC1=NC2=C(C=CC=C2)C3=C1N=C(CCCC)N3CCCCN.Cl.Cl.Cl
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Sung-Ju Moon, et al. Compositions containing, methods and uses of antibody-tlr agonist conjugates. Patent WO2020168017A1.
molnova catalog
related products
-
ODN 1826
ODN 1826 is a 20-mer DNA strand, a TLR9 agonist and an immunostimulant, with anti-tumor and cardioprotective effects, promoting apoptosis, and stimulating the production of NO and iNOS. ODN 1826 is a CpG DNA mimetic that can be used as an adjuvant for synthetic vaccines.
-
CU-CPT9b
CU-CPT9b is an antagonist of toll-like receptor 8 (TLR8;?Kd = 21 nM).?It inhibits activation of NF-?B induced by the TLR8 agonist R-848 in TLR8-overexpressing HEK-Blue cells with an IC50 value of 0.7 nM.
-
Isatoribine
Isatoribine (ANA245;7-Thia-8-oxoguanosine;Immunosine) is a nucleoside analogue, selective agonist of TLR7 with significant antiviral effect and mmunoenhancing activity.
