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Home - Products - Metabolic Enzyme/Protease - Xanthine Oxidase (XAO) - Xanthine oxidoreductase-IN-4

Xanthine oxidoreductase-IN-4

CAS No. 1026587-58-5

Xanthine oxidoreductase-IN-4( —— )

Catalog No. M36437 CAS No. 1026587-58-5

Xanthine oxidoreductase-IN-4 is an orally active xanthine oxidoreductase (XOR) inhibitor with an IC50 value of 29.3 nM, useful for studying hyperuricemia.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Xanthine oxidoreductase-IN-4
  • Note
    Research use only, not for human use.
  • Brief Description
    Xanthine oxidoreductase-IN-4 is an orally active xanthine oxidoreductase (XOR) inhibitor with an IC50 value of 29.3 nM, useful for studying hyperuricemia.
  • Description
    Xanthine oxidoreductase-IN-4 is an orally active xanthine oxidoreductase (XOR) inhibitor. Xanthine oxidoreductase-IN-4 has inhibitory activity against XOR with an IC50 value of 29.3 nM. Xanthine oxidoreductase-IN-4 can be used for the research of hyperuricemia.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Mice acute hyperuricemia modelDosage:5 mg/kg Administration:Oral Result:Reduced serum levels of uric acid significantly from 4 h after administration.
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Xanthine Oxidase (XAO)
  • Recptor
    Xanthine Oxidase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1026587-58-5
  • Formula Weight
    309.32
  • Molecular Formula
    C16H15N5O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(NC1=CC=C(OCC)C=C1)(=O)C2=CC=C(C=C2)C=3NN=NN3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Wen Peng, et al. Design, synthesis, and evaluation of tricyclic compounds containing phenyl-tetrazole as XOR inhibitors. Eur J Med Chem. 2022 Nov 28;246:114947. ?
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