Nizubaglustat
CAS No. 1633666-49-5
Nizubaglustat( —— )
Catalog No. M36337 CAS No. 1633666-49-5
Nizubaglustat (AZ3102) is an orally available, selective and brain-permeable dual inhibitor of ceramide glucosyltransferase and non-lysosomal glucosylceramide amidase (NLGase) for the study of neurological diseases.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 695 | Get Quote |
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| 5MG | 1007 | Get Quote |
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| 10MG | 1349 | Get Quote |
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| 25MG | 1950 | Get Quote |
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| 50MG | 2558 | Get Quote |
|
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameNizubaglustat
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NoteResearch use only, not for human use.
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Brief DescriptionNizubaglustat (AZ3102) is an orally available, selective and brain-permeable dual inhibitor of ceramide glucosyltransferase and non-lysosomal glucosylceramide amidase (NLGase) for the study of neurological diseases.
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DescriptionNizubaglustat is an inhibitor of Ceramide Glucosyltransferase or Glucosylceramide Synthase (GCS). Nizubaglustat also inhibits GBA2, involving in neuropathological lysosomal storage disorders.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetTransferase
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RecptorTransferase
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Research Area——
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Indication——
Chemical Information
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CAS Number1633666-49-5
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Formula Weight433.51
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Molecular FormulaC24H32FNO5
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Purity>98% (HPLC)
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Solubility——
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SMILESFC1=C(C=CC(COCCCCCN2[C@@H](CO)[C@@H](O)[C@H](O)[C@@H](O)C2)=C1)C3=CC=CC=C3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Ghisaidoobe AT, et al. Identification and development of biphenyl substituted iminosugars as improved dual glucosylceramide synthase/neutral glucosylceramidase inhibitors. J Med Chem. 2014 Nov 13;57(21):9096-104.?
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