Nizubaglustat( —— )

Catalog No. M36337 CAS No. 1633666-49-5

Nizubaglustat (AZ3102) is an orally available, selective and brain-permeable dual inhibitor of ceramide glucosyltransferase and non-lysosomal glucosylceramide amidase (NLGase) for the study of neurological diseases.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Size	Price / USD	Stock	Quantity
2MG	695	Get Quote
5MG	1007	Get Quote
10MG	1349	Get Quote
25MG	1950	Get Quote
50MG	2558	Get Quote
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Biological Information

Product Name

Nizubaglustat
Note

Research use only, not for human use.
Brief Description

Nizubaglustat (AZ3102) is an orally available, selective and brain-permeable dual inhibitor of ceramide glucosyltransferase and non-lysosomal glucosylceramide amidase (NLGase) for the study of neurological diseases.
Description

Nizubaglustat is an inhibitor of Ceramide Glucosyltransferase or Glucosylceramide Synthase (GCS). Nizubaglustat also inhibits GBA2, involving in neuropathological lysosomal storage disorders.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Metabolic Enzyme/Protease
Target

Transferase
Recptor

Transferase
Research Area

——
Indication

——

Chemical Information

CAS Number

1633666-49-5
Formula Weight

433.51
Molecular Formula

C24H32FNO5
Purity

>98% (HPLC)
Solubility

——
SMILES

FC1=C(C=CC(COCCCCCN2[C@@H](CO)[C@@H](O)[C@H](O)[C@@H](O)C2)=C1)C3=CC=CC=C3
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Ghisaidoobe AT, et al. Identification and development of biphenyl substituted iminosugars as improved dual glucosylceramide synthase/neutral glucosylceramidase inhibitors. J Med Chem. 2014 Nov 13;57(21):9096-104.?

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