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AGPS-IN-2i

CAS No. 2316782-88-2

AGPS-IN-2i( —— )

Catalog No. M36301 CAS No. 2316782-88-2

AGPS-IN-2i is a potent and high-affinity inhibitor of alkylglycerol phosphate synthase that controls ether lipid utilization and metabolism in cells, reduces ether lipid levels and cell migration, and promotes proliferation and motility of cancer cells.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 148 In Stock
5MG 188 In Stock
10MG 312 In Stock
25MG 524 In Stock
50MG 732 In Stock
100MG 995 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    AGPS-IN-2i
  • Note
    Research use only, not for human use.
  • Brief Description
    AGPS-IN-2i is a potent and high-affinity inhibitor of alkylglycerol phosphate synthase that controls ether lipid utilization and metabolism in cells, reduces ether lipid levels and cell migration, and promotes proliferation and motility of cancer cells.
  • Description
    AGPS-IN-1 (Compound 2i) is an effective AGPS binder. AGPS-IN-1 reduces ether lipids levels and cell migration rate. AGPS-IN-1 inhibits epithelial-mesenchymal transition (EMT) in prostate PC-3 and breast MDA-MB-231 cancer cells.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    MMP
  • Recptor
    MMP
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2316782-88-2
  • Formula Weight
    345.34
  • Molecular Formula
    C18H17F2N3O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(NC(CC(C)C1=C(F)C=CC=C1F)=O)C=2C=C3C(=CC2)NC(=O)N3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Stazi G, et al. Development of alkyl glycerone phosphate synthase inhibitors: Structure-activity relationship and effects on ether lipids and epithelial-mesenchymal transition in cancer cells. Eur J Med Chem. 2019 Feb 1;163:722-735.?
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