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Home - Products - Wnt/Notch/Hedgehog - Wnt/beta/catenin - YW2036

YW2036

CAS No. 2131223-92-0

YW2036( —— )

Catalog No. M36036 CAS No. 2131223-92-0

YW2036 is an inhibitor of Wnt signaling pathway.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 98 In Stock
10MG 148 In Stock
25MG 236 In Stock
50MG 326 In Stock
100MG 437 In Stock
200MG 581 In Stock
500MG Get Quote In Stock
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Biological Information

  • Product Name
    YW2036
  • Note
    Research use only, not for human use.
  • Brief Description
    YW2036 is an inhibitor of Wnt signaling pathway.
  • Description
    YW2036 (compound 2a) is a potent Wnt/β-Catenin signaling pathway inhibitor with an IC50 value of 637 nM. YW2036 can be used in research of cancer.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Wnt/Notch/Hedgehog
  • Target
    Wnt/beta/catenin
  • Recptor
    Wnt/beta-catenin
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2131223-92-0
  • Formula Weight
    328.37
  • Molecular Formula
    C20H16N4O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC=1N(N=CC1C(NC2=NC3=C(C=C2)C=CC=C3)=O)C4=CC=CC=C4
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Yang W, et, al. Pyrazole-4-Carboxamide (YW2065): A Therapeutic Candidate for Colorectal Cancer via Dual Activities of Wnt/β-Catenin Signaling Inhibition and AMP-Activated Protein Kinase (AMPK) Activation. J Med Chem. 2019 Dec 26;62(24):11151-11164. ?
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