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ICG-001
CAS No. 780757-88-2
ICG-001( —— )
Catalog No. M15944 CAS No. 780757-88-2
ICG-001 is an antagonist of Wnt/β-catenin/TCF-mediated transcription and specifically binds to element-binding protein (CBP) with IC50 of 3 μM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 74 | In Stock |
|
| 5MG | 61 | In Stock |
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| 10MG | 103 | In Stock |
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| 25MG | 207 | In Stock |
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| 50MG | 352 | In Stock |
|
| 100MG | 547 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 1172 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameICG-001
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NoteResearch use only, not for human use.
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Brief DescriptionICG-001 is an antagonist of Wnt/β-catenin/TCF-mediated transcription and specifically binds to element-binding protein (CBP) with IC50 of 3 μM.
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DescriptionICG-001 is an antagonist of Wnt/β-catenin/TCF-mediated transcription and specifically binds to element-binding protein (CBP) with IC50 of 3 μM.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayWnt/Notch/Hedgehog
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TargetWnt/beta/catenin
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RecptorIC50: 3 μM (CBP)
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number780757-88-2
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Formula Weight548.63
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Molecular FormulaC??H??N?O?
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESO=C(NCC1=CC=CC=C1)N2CCC(N([C@@]2(CN(C3=O)CC4=C5C=CC=CC5=CC=C4)[H])[C@H]3CC6=CC=C(C=C6)O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Yan D, et al, Leptin-induced epithelial-mesenchymal transition in breast cancer cells requires β-catenin activation via Akt/GSK3- and MTA1/Wnt1 protein-dependent pathways. J Biol Chem, 2012, 287(11), 8598-8612.
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