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HIF-1 inhibitor-4
CAS No. 333357-56-5
HIF-1 inhibitor-4( —— )
Catalog No. M35970 CAS No. 333357-56-5
HIF-1 inhibitor-4 (HIF-1 inhibitor-4) is a HIF-1 inhibitor with IC50 of 560 nM. HIF-1 inhibitor-4 reduces the HIF-1α protein level without affecting its mRNA level.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 112 | In Stock |
|
| 5MG | 92 | In Stock |
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| 10MG | 151 | In Stock |
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| 25MG | 281 | In Stock |
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| 50MG | 445 | In Stock |
|
| 100MG | 687 | In Stock |
|
| 200MG | 918 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameHIF-1 inhibitor-4
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NoteResearch use only, not for human use.
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Brief DescriptionHIF-1 inhibitor-4 (HIF-1 inhibitor-4) is a HIF-1 inhibitor with IC50 of 560 nM. HIF-1 inhibitor-4 reduces the HIF-1α protein level without affecting its mRNA level.
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DescriptionHIF-1 inhibitor-4 is a HIF-1 inhibitor (IC50: 560 nM). HIF-1 inhibitor-4 reduces the HIF-1α protein level without affecting its mRNA level.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayAngiogenesis
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TargetHIF/HIF Prolyl-hydroxylase
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RecptorHIF
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Research Area——
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Indication——
Chemical Information
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CAS Number333357-56-5
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Formula Weight422.26
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Molecular FormulaC18H19IN2O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 25 mg/mL (59.21 mM; Ultrasonic (<60°C)
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SMILESIC1=CC=C(NC(=O)C2=CC=C(CN3CCOCC3)C=C2)C=C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Nagao S, et al. Synthesis and structure-activity relationships of novel, potent, orally active hypoxia-inducible factor-1 inhibitors. Bioorg Med Chem. 2014 Oct 1;22(19):5513-29. ?
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