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hMAO-B-IN-4
CAS No. 1666119-75-0
hMAO-B-IN-4( —— )
Catalog No. M35968 CAS No. 1666119-75-0
hMAO-B-IN-4 is a selective, reversible and blood–brain barrier (BBB) penetrable inhibitor of human monoamine oxidase-B (hMAO-B, IC50=0.067 μM, Ki= 0.03 μM, hMAO-A, IC50= 33.82 μM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 42 | In Stock |
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| 5MG | 36 | In Stock |
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| 10MG | 55 | In Stock |
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| 25MG | 112 | In Stock |
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| 50MG | 183 | In Stock |
|
| 100MG | 300 | In Stock |
|
| 200MG | 428 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NamehMAO-B-IN-4
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NoteResearch use only, not for human use.
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Brief DescriptionhMAO-B-IN-4 is a selective, reversible and blood–brain barrier (BBB) penetrable inhibitor of human monoamine oxidase-B (hMAO-B, IC50=0.067 μM, Ki= 0.03 μM, hMAO-A, IC50= 33.82 μM).
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DescriptionhMAO-B-IN-4 (compound B10) is a selective, reversible and blood–brain barrier (BBB) penetrable human monoamine oxidase-B (hMAO-B) inhibitor with an IC50 value and a Ki value of 0.067 and 0.03 μM, respectively. hMAO-B-IN-4 inhibits hMAO-A with an IC50 value of 33.82 μM. hMAO-B-IN-4 can be used for Alzheimer’s disease (AD) and Parkinson’s disease (PD) research.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetMAO
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RecptorMAO
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Research Area——
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Indication——
Chemical Information
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CAS Number1666119-75-0
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Formula Weight320.4
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Molecular FormulaC20H16O2S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (156.05 mM; Ultrasonic )
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SMILESO=C(\C=C\c1ccc(OCc2ccccc2)cc1)c1cccs1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Sudevan ST, et al. Introduction of benzyloxy pharmacophore into aryl/heteroaryl chalcone motifs as a new class of monoamine oxidase B inhibitors. Sci Rep. 2022 Dec 27;12(1):22404.?
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