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Dual FAAH/sEH-IN-1

CAS No. 2756099-59-7

Dual FAAH/sEH-IN-1( —— )

Catalog No. M35726 CAS No. 2756099-59-7

Dual FAAH/sEH-IN-1 is a dual inhibitor of sEH (soluble epoxide hydrolase) (IC50: 9.6 nM) and FAAH (fatty acid amide hydrolase) (IC50: 7 nM) with high affinity and anti-inflammatory activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Dual FAAH/sEH-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    Dual FAAH/sEH-IN-1 is a dual inhibitor of sEH (soluble epoxide hydrolase) (IC50: 9.6 nM) and FAAH (fatty acid amide hydrolase) (IC50: 7 nM) with high affinity and anti-inflammatory activity.
  • Description
    Dual FAAH/sEH-IN-1 (compound 3) is a high affinity dual sEH (soluble epoxide hydrolase) and FAAH (fatty acid amide hydrolase) inhibitor, with IC50 values of 9.6 and 7 nM, respectively. Dual FAAH/sEH-IN-1 shows antinociception against the inflammatory phase.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    FAAH
  • Recptor
    FAAH | Epoxide Hydrolase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2756099-59-7
  • Formula Weight
    512.04
  • Molecular Formula
    C25H22ClN3O3S2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    N(C(=O)C1CCN(S(=O)(=O)C2=C(Cl)C=CC=C2)CC1)C3=CC=C(C4=NC=5C(S4)=CC=CC5)C=C3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Wilt S, Kodani S, Valencia L, et al. Further exploration of the structure-activity relationship of dual soluble epoxide hydrolase/fatty acid amide hydrolase inhibitors. Bioorg Med Chem. 2021;51:116507.?
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