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LSD1-IN-20
CAS No. 1239589-91-3
LSD1-IN-20( —— )
Catalog No. M35701 CAS No. 1239589-91-3
Lsd1-in-20 is a potent dual inhibitor of LSD1/G9a with Ki values of 0.44 and 0.68 μM, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 603 | Get Quote |
|
| 5MG | 922 | Get Quote |
|
| 10MG | 1121 | Get Quote |
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| 25MG | 1454 | Get Quote |
|
| 50MG | 1822 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameLSD1-IN-20
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NoteResearch use only, not for human use.
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Brief DescriptionLsd1-in-20 is a potent dual inhibitor of LSD1/G9a with Ki values of 0.44 and 0.68 μM, respectively.
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DescriptionLSD1-IN-20 (compound 1) is a potent dual non-covalent LSD1/G9a inhibitor, with Ki values of 0.44 and 0.68 μM, respectively. LSD1-IN-20 shows antiproliferative activity in THP-1 leukemia cells and MDA-MB-231 breast cancer cells, with IC50 (72 h) of 0.51 and 1.60 μM, respectively.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayChromatin/Epigenetic
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TargetHistone Demethylase
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RecptorHistone Demethylase
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Research Area——
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Indication——
Chemical Information
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CAS Number1239589-91-3
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Formula Weight478.63
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Molecular FormulaC27H38N6O2
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Purity>98% (HPLC)
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Solubility——
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SMILESN(C=1C2=C(N=C(NCCCN(C)C)N1)C=C(OC)C(OC)=C2)C3CCN(CC4=CC=CC=C4)CC3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Menna M, et al. Novel non-covalent LSD1 inhibitors endowed with anticancer effects in leukemia and solid tumor cellular models. Eur J Med Chem. 2022 Jul 5;237:114410.?
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