SD49-7

CAS No. 54009-54-0

SD49-7( —— )

Catalog No. M35980 CAS No. 54009-54-0

SD49-7 is an inhibitor of histone lysine demethylase 4 (KDM4) with an IC50 of 0.19 μM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 144 In Stock
5MG 126 In Stock
10MG 188 In Stock
25MG 378 In Stock
50MG 538 In Stock
100MG 769 In Stock
200MG Get Quote In Stock
500MG 1535 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    SD49-7
  • Note
    Research use only, not for human use.
  • Brief Description
    SD49-7 is an inhibitor of histone lysine demethylase 4 (KDM4) with an IC50 of 0.19 μM.
  • Description
    (E/Z)-NSAH is an isoform of NSAH (HY-114503), which is reversible and competitive nonnucleoside ribonucleotide reductase (RR) inhibitor, with cell-free IC50 of 32 μM and cell-based IC50 of ~250 nM, respectively.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Chromatin/Epigenetic
  • Target
    Histone Demethylase
  • Recptor
    Histone Demethylase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    54009-54-0
  • Formula Weight
    306.32
  • Molecular Formula
    C18H14N2O3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(=NNC(=O)C1=C(O)C=CC=C1)C=2C3=C(C=CC2O)C=CC=C3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Md Faiz Ahmad, et al. Potent competitive inhibition of human ribonucleotide reductase by a nonnucleoside small molecule. Proc Natl Acad Sci U S A. 2017 Aug 1;114(31):8241-8246.?
molnova catalog
related products
  • KDM4-IN-4

    KDM4-IN-4 (compound 47) is a potent inhibitor of histone lysine demethylase 4 (KDM4), with a binding constant of approximately 80 μM for the KDM4A-Tudor domain.

  • KDM5-C70

    KDM5-C70 is the cell-permeable derivative of KDM5-C49, potent, selective and cell permeable KDM5 inhibitor with IC50 of 0.3, 0.3 and 0.58 uM for KDM5A, B and C, respectively.

  • NCGC00244536

    NCGC00244536 is a potent KDM4B inhibitor (IC50: 10 nM).NCGC00244536 effectively inhibits AR-positive cell lines.