Cart
sales@molnova.com
Home - Products - Neuroscience - Gamma-secretase - γ-Secretase modulator 13

γ-Secretase modulator 13

CAS No. 1353570-40-7

γ-Secretase modulator 13( —— )

Catalog No. M35626 CAS No. 1353570-40-7

γ-Secretase modulator 13 is a γ-secretase modulator (GSMs) that inhibits the production of amyloid β-peptide Aβ42 and can be used to study Alzheimer's disease and tumors.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 445 Get Quote
5MG 686 Get Quote
10MG 938 Get Quote
25MG 1398 Get Quote
50MG 1822 Get Quote
100MG 2250 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    γ-Secretase modulator 13
  • Note
    Research use only, not for human use.
  • Brief Description
    γ-Secretase modulator 13 is a γ-secretase modulator (GSMs) that inhibits the production of amyloid β-peptide Aβ42 and can be used to study Alzheimer's disease and tumors.
  • Description
    γ-Secretase modulator 13 (compound 4) is a gamma-secretase modulator (GSMs) that inhibits the production of the aggregated amyloid β-peptide Aβ42 with an IC50 value of 163 nM. γ-Secretase modulator 13 can be used in the study of Alzheimer's disease.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Neuroscience
  • Target
    Gamma-secretase
  • Recptor
    Gamma-secretase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1353570-40-7
  • Formula Weight
    422.52
  • Molecular Formula
    C22H23FN6S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    FC=1C=C(C=CC1N2C=NC(=C2)C)C=3N=C(SC3)NC4=C5C(=NN4CC)CCCC5
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kevin D Rynearson, et al. Design and synthesis of novel methoxypyridine-derived gamma-secretase modulators. Bioorg Med Chem. 2020 Nov 15;28(22):115734.?
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Aβ42-IN-2

    Aβ42-IN-2, a γ-secretase modulator with an IC50 of 6.5 nM for Αβ42, can be used for Alzheimer's disease research .

  • RO7185876

    RO7185876 is a selective gamma secretase modulator, which can be used in the study of Alzheimer's disease.

  • MRK-560

    MRK-560 is an effective and brain-penetrant inhibitor of γ-secretase.

Sign In Join Free